Echovirus 1 endocytosis into caveosomes requires lipid rafts, dynamin II, and signaling events.

@article{Pietiinen2004Echovirus1E,
  title={Echovirus 1 endocytosis into caveosomes requires lipid rafts, dynamin II, and signaling events.},
  author={Vilja M Pieti{\"a}inen and Varpu S Marjom{\"a}ki and Paula Upla and Lucas Pelkmans and Ari Helenius and Timo Hyypi{\"a}},
  journal={Molecular biology of the cell},
  year={2004},
  volume={15 11},
  pages={
          4911-25
        }
}
Binding of echovirus 1 (EV1, a nonenveloped RNA virus) to the alpha2beta1 integrin on the cell surface is followed by endocytic internalization of the virus together with the receptor. Here, video-enhanced live microscopy revealed the rapid uptake of fluorescently labeled EV1 into mobile, intracellular structures, positive for green fluorescent protein-tagged caveolin-1. Partial colocalization of EV1 with SV40 (SV40) and cholera toxin, known to traffic via caveosomes, demonstrated that the… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 56 references

Poliovirus cell entry: common structural themes in viral cell entry pathways.

Annual review of microbiology • 2002
View 4 Excerpts
Highly Influenced

Lipid rafts and signal transduction

Nature Reviews Molecular Cell Biology • 2000
View 4 Excerpts
Highly Influenced

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