Echogenicity of the substantia nigra: association with increased iron content and marker for susceptibility to nigrostriatal injury.

@article{Berg2002EchogenicityOT,
  title={Echogenicity of the substantia nigra: association with increased iron content and marker for susceptibility to nigrostriatal injury.},
  author={Daniela Berg and Wolfgang Roggendorf and Ute Schroeder and R{\"u}diger Klein and Thomas Tatschner and Peter Benz and Oliver Tucha and Michael Preier and Klaus W. Lange and Karlheinz Reiners and Manfred Gerlach and G. Becker},
  journal={Archives of neurology},
  year={2002},
  volume={59 6},
  pages={
          999-1005
        }
}
BACKGROUND Patients with Parkinson disease characteristically exhibit an increased echogenicity of the substantia nigra (SN) on transcranial sonography, a new neuroimaging technique. The same echo feature of the SN can be identified in 9% of healthy adults. OBJECTIVE To evaluate the relevance of the echogenic SN in healthy adults. DESIGN In the first part of the study, 10 healthy subjects younger than 40 years with a distinct SN hyperechogenicity underwent extensive neurological, motor… CONTINUE READING
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