Echinohalimane A, a Bioactive Halimane-Type Diterpenoid from a Formosan Gorgonian Echinomuricea sp. (Plexauridae)

@inproceedings{Chung2012EchinohalimaneAA,
  title={Echinohalimane A, a Bioactive Halimane-Type Diterpenoid from a Formosan Gorgonian Echinomuricea sp. (Plexauridae)},
  author={Hsu-Ming Chung and Li-Chung Hu and Wei-Hsuan Yen and Jui-hsin Su and Mei-Chin Lu and Tsong-Long Hwang and Wei-Hsien Wang and Ping-Jyun Sung},
  booktitle={Marine drugs},
  year={2012}
}
A new halimane-type diterpenoid, echinohalimane A (1), was isolated from a gorgonian, identified as Echinomuricea sp. The structure of 1 was determined by spectroscopic methods and this compound was found to exhibit cytotoxicity toward various tumor cells and display an inhibitory effect on the release of elastase by human neutrophils. Echinohalimane A (1) is the first halimane analogue from the marine organisms belonging to phylum Cnidaria. 
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