Echinoclerodane A: A New Bioactive Clerodane-Type Diterpenoid from a Gorgonian Coral Echinomuricea sp

  title={Echinoclerodane A: A New Bioactive Clerodane-Type Diterpenoid from a Gorgonian Coral Echinomuricea sp},
  author={Ching-Hsiao Cheng and H. Chung and T. Hwang and M. Lu and Zhi-Hong Wen and Y. Kuo and W. Wang and P. Sung},
  pages={9443 - 9450}
  • Ching-Hsiao Cheng, H. Chung, +5 authors P. Sung
  • Published 2012
  • Biology, Medicine
  • Molecules
  • A new clerodane-type diterpenoid, echinoclerodane A (1), was isolated from a Formosan gorgonian coral Echinomuricea sp. The structure of 1 was elucidated by spectroscopic methods. Echinoclerodane A (1) is the first clerodane-type compound obtained from the marine organisms belonging to the phylum Cnidaria. Echinoclerodane A (1) exhibited moderate cytotoxicity toward MOLT-4, HL-60, DLD-1 and LoVo tumor cells and inhibitory effects on the generation of superoxide anion and the release of elastase… CONTINUE READING
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