Echinocandins: are they all the same?

  title={Echinocandins: are they all the same?},
  author={Pranab K Mukherjee and David Sheehan and Laura A. Puzniak and H Schlamm and Mahmoud Afif Ghannoum},
  journal={Journal of chemotherapy},
  volume={23 6},
The discovery of echinocandins, and their development and approval, was hailed as a significant addition to our antifungal armamentarium, previously predominated by polyenes and azoles. To date, three echinocandins (anidulafungin, caspofungin, and micafungin) have been approved by the U.S. Food and Drug Administration for the treatment of fungal infections. Since all three echinocandins target the fungal cell wall and share a similar structural chemical backbone, they are perceived to be… CONTINUE READING

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