Echinocandin resistance: an emerging clinical problem?

  title={Echinocandin resistance: an emerging clinical problem?},
  author={Maiken Cavling Arendrup and David Scott Perlin},
  journal={Current opinion in infectious diseases},
  volume={27 6},
PURPOSE OF REVIEW Echinocandin resistance in Candida is a great concern, as the echinocandin drugs are recommended as first-line therapy for patients with invasive candidiasis. Here, we review recent advances in our understanding of the epidemiology, underlying mechanisms, methods for detection and clinical implications. RECENT FINDINGS Echinocandin resistance has emerged over the recent years. It has been found in most clinically relevant Candida spp., but is most common in C. glabrata with… CONTINUE READING
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