Ecdysone-modulated response of Drosophila cytosolic malate dehydrogenase to juvenile hormone.

@article{Farka1997EcdysonemodulatedRO,
  title={Ecdysone-modulated response of Drosophila cytosolic malate dehydrogenase to juvenile hormone.},
  author={Robert Farka{\vs} and Jan Knopp},
  journal={Archives of insect biochemistry and physiology},
  year={1997},
  volume={35 1-2},
  pages={
          71-83
        }
}
Recently, we found that the activity of malate dehydrogenase (MDH), one of the key enzymes in the biosynthesis of lipids, is regulated in Drosophila melanogaster by juvenile hormone (JH) and JH analogues. Here we report that the response of MDH to JH, however, depends on the developmental stage of the animal in relation to its endogenous titre of ecdysteroids. During the interecdysial period of the last instar, when endogenous ecdysteroids are low, MDH rapidly responded to JH by increasing… CONTINUE READING

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