Eccrine Sweat Gland Involvement in GM1 Gangliosidosis

@article{Drut1978EccrineSG,
  title={Eccrine Sweat Gland Involvement in GM1 Gangliosidosis},
  author={Ricardo Drut},
  journal={Journal of Cutaneous Pathology},
  year={1978},
  volume={5}
}
  • R. Drut
  • Published 1 February 1978
  • Medicine
  • Journal of Cutaneous Pathology
This report describes eccrine sweat gland involvement in a patient with GM1 gangliosidosis. A striking vacuolization was noticed in cells of the acrosyringium and of the secretory coils. The diagnostic value of a skin biopsy in this condition is emphasized. 
4 Citations
Nonneoplastic disorders of the eccrine glands.
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This article summarizes current knowledge of eccrine gland pathophysiology and suggests that the excretion of drugs into eccrine sweat may be a contributory factor in neutrophilic eccrine hidradenitis, syringosquamous metaplasia, coma bulla, and erythema multiforme. Expand

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The histochemical and ultrastructural features support the chemical findings and indicate a quantitative and morphologic difference in storage between the two types of gangliosidosis, and may provide an additional diagnostic parameter in the delineation of the two clinical variants. Expand
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