Eccentric exercise-induced muscle damage impairs muscle glycogen repletion.

  title={Eccentric exercise-induced muscle damage impairs muscle glycogen repletion.},
  author={Kate O'Reilly and Michael Warhol and Roger A Fielding and Walter R. Frontera and Carol Meredith and William J Evans},
  journal={Journal of applied physiology},
  volume={63 1},
Five healthy untrained young male subjects were studied before, immediately after, and 10 days after a 45-min bout of eccentric exercise on a cycle ergometer (201 W). The subjects were sedentary at all other times and consumed a eucaloric meat-free diet. Needle biopsies of the vastus lateralis muscle were examined for intracellular damage and glycogen content. Immediately after exercise, muscle samples showed myofibrillar tearing and edema. At 10 days, there was myofibrillar necrosis… CONTINUE READING