Eccentric contraction-induced myofiber growth in tumor-bearing mice.

@article{Hardee2016EccentricCM,
  title={Eccentric contraction-induced myofiber growth in tumor-bearing mice.},
  author={Justin P Hardee and Joshua E. Mangum and Song Gao and Shuichi Sato and Kimbell Louise Hetzler and Melissa J. Puppa and Dennis K Fix and James A Carson},
  journal={Journal of applied physiology},
  year={2016},
  volume={120 1},
  pages={
          29-37
        }
}
Cancer cachexia is characterized by the progressive loss of skeletal muscle mass. While mouse skeletal muscle's response to an acute bout of stimulated low-frequency concentric muscle contractions is disrupted by cachexia, gaps remain in our understanding of cachexia's effects on eccentric contraction-induced muscle growth. The purpose of this study was to determine whether repeated bouts of stimulated high-frequency eccentric muscle contractions [high-frequency electrical muscle stimulation… CONTINUE READING
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