Ebola virus glycoprotein Fc fusion protein confers protection against lethal challenge in vaccinated mice.

@article{Konduru2011EbolaVG,
  title={Ebola virus glycoprotein Fc fusion protein confers protection against lethal challenge in vaccinated mice.},
  author={Krishnamurthy Konduru and Steven B. Bradfute and J{\'e}r{\^o}me Jacques and Mohanraj Manangeeswaran and Siham M Nakamura and Sufi Morshed and Steven C. Wood and Sina Bavari and Gerardo G. Kaplan},
  journal={Vaccine},
  year={2011},
  volume={29 16},
  pages={2968-77}
}
Ebola virus is a Filoviridae that causes hemorrhagic fever in humans and induces high morbidity and mortality rates. Filoviruses are classified as "Category A bioterrorism agents", and currently there are no licensed therapeutics or vaccines to treat and prevent infection. The Filovirus glycoprotein (GP) is sufficient to protect individuals against infection, and several vaccines based on GP are under development including recombinant adenovirus, parainfluenza virus, Venezuelan equine… CONTINUE READING
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