Ebola virus : the role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever , The International Journal of Biochemistry and Cell Biology

  • Mike Braya, Thomas W. Geisbertb
  • Published 2005

Abstract

Ebola hemorrhagic fever is a severe viral infection characterized by fever, shock and coagulation defects. Recent studies in macaques show that major features of illness are caused by effects of viral replication on macrophages and dendritic cells. Infected macrophages produce proinflammatory cytokines, chemokines and tissue factor, attracting additional… (More)

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