Eating high fat chow and the behavioral effects of direct-acting and indirect-acting dopamine receptor agonists in female rats.

@article{Serafine2014EatingHF,
  title={Eating high fat chow and the behavioral effects of direct-acting and indirect-acting dopamine receptor agonists in female rats.},
  author={Katherine M Serafine and Todd A Bentley and Amandine E Grenier and Charles P France},
  journal={Behavioural pharmacology},
  year={2014},
  volume={25 4},
  pages={287-95}
}
Eating high fat chow increases the sensitivity of male rats to some behavioral effects of the direct-acting dopamine receptor agonist quinpirole; it is not known whether sensitivity to quinpirole is similarly enhanced in female rats eating high fat chow. Female Sprague-Dawley rats had free access to standard chow (5.7% fat) or either free or restricted access (i.e. body weight matched to rats eating standard chow) to high fat (34.3% fat) chow. Quinpirole (0.0032-0.32 mg/kg) produced hypothermia… CONTINUE READING