Eating disorders, gene–environment interactions and epigenetics

@article{Campbell2011EatingDG,
  title={Eating disorders, gene–environment interactions and epigenetics},
  author={Iain C. Campbell and Jonathan Mill and Rudolf Uher and Ulrike Schmidt},
  journal={Neuroscience \& Biobehavioral Reviews},
  year={2011},
  volume={35},
  pages={784-793}
}
This review describes the various subtypes of eating disorders and examines factors associated with the risk of illness. It considers evidence that the development and maintenance of eating disorders is due to gene-environment interactions (GxE) that alter genetic expression via epigenetic processes. It describes how environmental factors such as those associated with nutrition and/or stress may cause epigenetic changes which have transcriptional and phenotypic effects, which, in turn, alter… 
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It is suggested that epigenetics could provide new insights into a more comprehensive interpretation of mental illness and might eventually improve the nosology, treatment, and prevention of psychiatric disorders.
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An in-depth review of the scientific literature on the genetics of anorexia nervosa, BN, and BED including extant studies, emerging hypotheses, future directions, and clinical implications is provided.
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Knowledge of epigenetic mechanisms may help shed new light on the origin of maturational phenotypes underlying eating disorders and why adjusting treatments to these realities warrants the authors' attention.
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