Eating, exercise, and "thrifty" genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases.

@article{Chakravarthy2004EatingEA,
  title={Eating, exercise, and "thrifty" genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases.},
  author={M. Chakravarthy and F. Booth},
  journal={Journal of applied physiology},
  year={2004},
  volume={96 1},
  pages={
          3-10
        }
}
Survival of Homo sapiens during evolution was dependent on the procurement of food, which in turn was dependent on physical activity. However, food supply was never consistent. Thus it is contended that the ancient hunter-gatherer had cycles of feast and famine, punctuated with obligate periods of physical activity and rest. Hence, gene selection in the Late-Paleolithic era was probably influenced by physical activity and rest. To ensure survival during periods of famine, certain genes evolved… Expand
Evolutionary origins of obesity
  • A. Bellisari
  • Biology, Medicine
  • Obesity reviews : an official journal of the International Association for the Study of Obesity
  • 2008
The contribution of psychosocial stress to the obesity epidemic: an evolutionary approach.
  • M. Siervo, J. Wells, G. Cizza
  • Biology, Medicine
  • Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
  • 2009
On the evolutionary origins of obesity: a new hypothesis.
Evolutionary perspectives on the obesity epidemic: adaptive, maladaptive, and neutral viewpoints.
  • J. Speakman
  • Biology, Medicine
  • Annual review of nutrition
  • 2013
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 58 REFERENCES
Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy.
Physical activity, energy expenditure and fitness: an evolutionary perspective.
Evolutionary health promotion.
Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?
  • J. Neel
  • Biology, Medicine
  • American journal of human genetics
  • 1962
J.B. Wolffe Memorial Lecture. "Why exercise?".
  • P. Åstrand
  • Medicine
  • Medicine and science in sports and exercise
  • 1992
How is Darwinian medicine useful?
  • R. Nesse
  • Biology, Medicine
  • The Western journal of medicine
  • 2001
Exercise training increases lipid metabolism gene expression in human skeletal muscle.
Fasting activates the gene expression of UCP3 independent of genes necessary for lipid transport and oxidation in skeletal muscle.
...
1
2
3
4
5
...