• DOI:10.1152/JAPPLPHYSIOL.00757.2003
Corpus ID: 5817629

Eating, exercise, and "thrifty" genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases.

@article{Chakravarthy2004EatingEA,
  title={Eating, exercise, and "thrifty" genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases.},
  author={M. Chakravarthy and F. Booth},
  journal={Journal of applied physiology},
  year={2004},
  volume={96 1},
  pages={
          3-10
        }
}

• M. Chakravarthy, F. Booth
• Published 2004
• Biology, Medicine
• Journal of applied physiology

Survival of Homo sapiens during evolution was dependent on the procurement of food, which in turn was dependent on physical activity. However, food supply was never consistent. Thus it is contended that the ancient hunter-gatherer had cycles of feast and famine, punctuated with obligate periods of physical activity and rest. Hence, gene selection in the Late-Paleolithic era was probably influenced by physical activity and rest. To ensure survival during periods of famine, certain genes evolved… Expand