East Practice Management Guidelines Work Group: update to practice management guidelines for prophylactic antibiotic use in open fractures.

@article{Hoff2011EastPM,
  title={East Practice Management Guidelines Work Group: update to practice management guidelines for prophylactic antibiotic use in open fractures.},
  author={William S. Hoff and John A Bonadies and Riad Cachecho and Warren C. Dorlac},
  journal={The Journal of trauma},
  year={2011},
  volume={70 3},
  pages={
          751-4
        }
}
STATEMENT OF THE PROBLEMAn open fracture is defined as one in which the fracture fragments communicate with the environment through a break in the skin. The presence of an open fracture either isolated or as part of a multiple injury complex increases the risk of infection and soft tissue complicati 
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148 Citations
Highly Influential Citations
8
Background Citations
31
Methods Citations
8

148 Citations

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Citation Type

Evidence-based review: management of open pediatric fractures.
TLDR
A review of the available literature finds that open pediatric fractures have better outcomes than open fractures in adults and gives corresponding recommendations based on the level of evidence.
Antibiotic Prophylaxis for Open Fractures in the Emergency Department
TLDR
This review will discuss the etiology and factors associated with the development of infections in this setting, the use of empiric antibiotics, and the guidelines currently available.
Timing of Operative Debridement in Open Fractures.
Open Fractures: Initial Management
TLDR
Dependence on the patient’s condition and local injury pattern, fracture stabilization should be performed with external or internal stabilization devices, and in type I and II injuries primary wound closure is possible, in type III injuries temporary wound closure using negative-pressure wound therapy should be performing.
Update in Therapeutics: Prophylactic Antibiotics in Open Fractures.
TLDR
Recommendations for antibiotic regimens for all Gustilo-Anderson fracture grades include first-, second-, and third-generation cephalosporins.
Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations.
TLDR
The Gustilo-Anderson classification of open fractures has been used to guide prophylactic antibiotic therapy because different types of open fracture have been shown to have varying rates of surgical site infections with different combinations of pathogens.
Effect of COVID-19 on surgical management of open fractures and infection rates: A tertiary care experience in Indian set-up
Controversies in the Management of Open Fractures
TLDR
Exploration of controversies around the most appropriate soft tissue management approach for open fractures – immediate definitive soft tissue closure versus leaving wounds open for delayed closure or definitive management – is also an area of debate.
Impact of an emergency medicine pharmacist on initial antibiotic prophylaxis for open fractures in trauma patients
Compliance and Related Outcomes of Prophylactic Antibiotics in Traumatic Open Fractures
Purpose: Prophylactic antibiotic therapy is a standard of care for patients who present with open fractures due to the risk of infectious complications. This study was conducted to characterize the…
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References

SHOWING 1-10 OF 86 REFERENCES
Effect of Time Delay from Injury to Primary Management on the Incidence of Deep Infection After Open Fractures of the Lower Extremities Caused by Blunt Trauma in Adults
TLDR
It is suggested that delay within the first 24 h after injury may not have a significant prognostic influence on the subsequent frequency of late deep infection in patients otherwise treated optimally.
Treatment of open fractures of the foot and ankle: a preliminary report.
  • A. Acello, G. Wallace, N. Pachuda
  • Medicine
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Use of antibiotics in open tibial fractures.
TLDR
The highest infection rate was in open tibiae receiving no antibiotics, and the lowest was in the group receiving a cephalosporin and an aminoglycoside (4.5%, 5 infections in 109 open tibia fracture wounds).
Role of antibiotics in open fractures of the finger.
Practice management guidelines for trauma from the Eastern Association for the Surgery of Trauma.
Clinical practice guidelines are being used as a means of reducing inappropriate care, controlling geographic variations in practice patterns, and making more effective use of health care resources.…
Antibiotics in open fractures of the distal phalanx?
Factors influencing infection rate in open fracture wounds.
TLDR
The single most important factor in reducing the infection rate was the early administration of antibiotics that provide antibacterial activity against both gram-positive and gram-negative microorganisms.
Antibiotic prophylaxis in orthopaedic surgery.
  • C. Court-Brown
  • Medicine
    Scandinavian journal of infectious diseases. Supplementum
  • 1990
TLDR
Its usefulness has been well demonstrated in joint replacement surgery although further work is required in traumatic orthopaedics, and further investigation is required into the side effects and cost benefits of prophylaxis.
Primary or delayed closure for open tibial fractures.
TLDR
It is concluded that primary wound closure should be avoided in the treatment of open tibial fractures.
The effect of surgical delay on acute infection following 554 open fractures in children.
TLDR
The findings of the present study suggest that, in children who receive early antibiotic therapy following an open fracture, surgical debridement within six hours after the injury offers little benefit over debridements within twenty-four hours afterThe injury with regard to the prevention of acute infection.
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