Earthworms and humans in vitro: characterizing evolutionarily conserved stress and immune responses to silver nanoparticles.

@article{Hayashi2012EarthwormsAH,
  title={Earthworms and humans in vitro: characterizing evolutionarily conserved stress and immune responses to silver nanoparticles.},
  author={Yuya Hayashi and P{\'e}ter Engelmann and Rasmus Foldbjerg and Mariann Szab{\'o} and Ildik{\'o} Somogyi and Edit Poll{\'a}k and L{\'a}szl{\'o} Moln{\'a}r and Herman Autrup and Duncan S Sutherland and Janeck J Scott-Fordsmand and Lars-Henrik Heckmann},
  journal={Environmental science & technology},
  year={2012},
  volume={46 7},
  pages={4166-73}
}
Little is known about the potential threats of silver nanoparticles (AgNPs) to ecosystem health, with no detailed report existing on the stress and immune responses of soil invertebrates. Here we use earthworm primary cells, cross-referencing to human cell cultures with a particular emphasis on the conserved biological processes, and provide the first in vitro analysis of molecular and cellular toxicity mechanisms in the earthworm Eisenia fetida exposed to AgNPs (83 ± 22 nm). While we observed… CONTINUE READING