Early x-ray hypoattenuation of brain parenchyma indicates extended critical hypoperfusion in acute stroke.

@article{Grond2000EarlyXH,
  title={Early x-ray hypoattenuation of brain parenchyma indicates extended critical hypoperfusion in acute stroke.},
  author={Martin Grond and R{\"u}diger von Kummer and Jan Sobesky and Susanne Schm{\"u}lling and Jobst Rudolf and Klaus Terstegge and W-D Heiss},
  journal={Stroke},
  year={2000},
  volume={31 1},
  pages={133-9}
}
BACKGROUND AND PURPOSE The presence of early x-ray hypoattenuation is an important selection criterion for thrombolytic therapy. However, knowledge about the pathophysiological constellation reflected by this hypoattenuation is lacking. Our objective was to study the relationship between the presence of early CT hypoattenuation and the volumes of critical cortical hypoperfusion. METHODS In 32 patients with acute ischemic stroke, CT was performed 20 to 170 minutes (mean, 94 minutes) after… CONTINUE READING