Early versus late surgical intervention or medical management for infective endocarditis: a systematic review and meta-analysis

@article{Narayanan2016EarlyVL,
  title={Early versus late surgical intervention or medical management for infective endocarditis: a systematic review and meta-analysis},
  author={Mahesh Anantha Narayanan and Toufik Mahfood Haddad and A. Kalil and Arun Kanmanthareddy and R. Suri and G. Mansour and C. Destache and Janani Baskaran and A. Mooss and T. Wichman and L. Morrow and R. Vivekanandan},
  journal={Heart},
  year={2016},
  volume={102},
  pages={950 - 957}
}
Objective Infective endocarditis is associated with high morbidity and mortality and optimal timing for surgical intervention is unclear. We performed a systematic review and meta-analysis to compare early surgical intervention with conservative therapy in patients with infective endocarditis. Methods PubMed, Cochrane, EMBASE, CINAHL and Google-scholar databases were searched from January 1960 to April 2015. Randomised controlled trials, retrospective cohorts and prospective observational… Expand
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