Early versus late hormonal therapy: debating the issues.

  title={Early versus late hormonal therapy: debating the issues.},
  author={E. David Crawford},
  volume={61 2 Suppl 1},
Hormonal therapy for prostate cancer has traditionally been reserved for advanced disease, but current evidence suggests that earlier use can confer a survival advantage. Survival benefit has been observed among patients with TNM stage T3 tumors who were treated with hormonal therapy plus external irradiation. Patients with nodal metastases (D1) who received immediate treatment with hormonal therapy after radical prostatectomy and pelvic lymphadenectomy also survived longer than those who were… CONTINUE READING