Early vascular and neuronal changes in a VEGF transgenic mouse model of retinal neovascularization.

Abstract

PURPOSE To investigate early retinal changes in a vascular endothelial growth factor (VEGF) transgenic mouse (tr029VEGF; rhodopsin promoter) with long-term damage that mimics nonproliferative diabetic retinopathy (NPDR) and mild proliferative diabetic retinopathy (PDR). METHODS Rhodopsin and VEGF expression was assessed up to postnatal day (P)28. Vascular… (More)

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