Early tumor detection afforded by in vivo imaging of near-infrared II fluorescence.

Abstract

Cell-intrinsic reporters such as luciferase (LUC) and red fluorescent protein (RFP) have been commonly utilized in preclinical studies to image tumor growth and to monitor therapeutic responses. While extrinsic reporters that emit near infrared I (NIR-I: 650-950 nm) or near-infrared II (NIR-II: 1000-1700 nm) optical signals have enabled minimization of… (More)
DOI: 10.1016/j.biomaterials.2017.04.046

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