Early trypsin activity is part of the signal transduction system that activates transcription of the late trypsin gene in the midgut of the mosquito, Aedes aegypti.

@article{BARILLASMURY1995EarlyTA,
  title={Early trypsin activity is part of the signal transduction system that activates transcription of the late trypsin gene in the midgut of the mosquito, Aedes aegypti.},
  author={CAROLINA V. BARILLAS-MURY and Fernando Gabriel Noriega and Michael R. Wells},
  journal={Insect biochemistry and molecular biology},
  year={1995},
  volume={25 2},
  pages={241-6}
}
Trypsin activity during the first hours after feeding is essential to induce late trypsin gene expression. These results are consistent with the idea that free amino acids or other products released during digestion might be the initial signal for transcriptional activation of late trypsin. Besides early trypsin, some other factor(s) have to be translated for induction of late trypsin. This is the first case in which the proteolytic activity of a digestive enzyme is part of the signal… CONTINUE READING