Early suppressive mechanisms and the negative blood oxygenation level-dependent response in human visual cortex.

@article{Wade2010EarlySM,
  title={Early suppressive mechanisms and the negative blood oxygenation level-dependent response in human visual cortex.},
  author={Alex R. Wade and Jess Rowland},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2010},
  volume={30 14},
  pages={5008-19}
}
Functional magnetic resonance imaging (fMRI) studies of early sensory cortex often measure stimulus-driven increases in the blood oxygenation level-dependent (BOLD) signal. However, these positive responses are frequently accompanied by reductions in the BOLD signal in adjacent regions of cortex. Although this negative BOLD response (NBR) is thought to result from neuronal suppression, the precise relationship between local activity, suppression, and perception remains unknown. By measuring… CONTINUE READING

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