Early stress protein gene expression in a human model of ischemic preconditioning.

@article{Patel2004EarlySP,
  title={Early stress protein gene expression in a human model of ischemic preconditioning.},
  author={Anisha B. Patel and Marcel C. G. van de Poll and Jan Willem W. M. Greve and Wim A. Buurman and Kenneth C. H. Fearon and Stephen J McNally and Ewen M Harrison and James Alexander Ross and Oliver J Garden and Cornelius H. C. Dejong and Stephen J. Wigmore},
  journal={Transplantation},
  year={2004},
  volume={78 10},
  pages={1479-87}
}
Intermittent clamping of the porta hepatis (PHC) is commonly performed during liver surgery to reduce blood loss and has been reported to precondition livers resulting in improved outcome after liver surgery (humans) and transplantation (animals). This study investigated the early expression of cytoprotective stress proteins during ischemia-reperfusion induced by PHC. Liver samples were taken before and after each event in a two-cycle ischemia-reperfusion protocol using 15 minutes of PHC… CONTINUE READING

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