Early steps in reovirus infection are associated with dramatic changes in supramolecular structure and protein conformation: analysis of virions and subviral particles by cryoelectron microscopy and image reconstruction

@article{Dryden1993EarlySI,
  title={Early steps in reovirus infection are associated with dramatic changes in supramolecular structure and protein conformation: analysis of virions and subviral particles by cryoelectron microscopy and image reconstruction},
  author={Kelly Dryden and Gongbo Wang and Mark Yeager and Max L Nibert and Katie Marie Coombs and D B Furlong and Bernard Nathan Fields and Timothy S. Baker},
  journal={The Journal of Cell Biology},
  year={1993},
  volume={122},
  pages={1023 - 1041}
}
Three structural forms of type 1 Lang reovirus (virions, intermediate subviral particles [ISVPs], and cores) have been examined by cryoelectron microscopy (cryoEM) and image reconstruction at 27 to 32-A resolution. Analysis of the three-dimensional maps and known biochemical composition allows determination of capsid protein location, globular shape, stoichiometry, quaternary organization, and interactions with adjacent capsid proteins. Comparisons of the virion, ISVP and core structures and… CONTINUE READING
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Sigma I protein

  • D. B. Furlong, M. L. Nibert, B. N. Fields
  • 1988
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9 Excerpts

A cerboxy-teminal fragment of protein /~l//t 1C is present in infectious subvirion particles of mammalian reoviruses and is proposed to have a role in penetration..

  • M. L. Nihert, B. N. Fields
  • Virol
  • 1992

Cryo-electron microscopy and three-dimensional image reconstruction of icosahedral viruses

  • T. S. Baker
  • Prec. 10
  • 1992
2 Excerpts

Reovirus polypeptide o3 and N-terminal

  • L. Tillotson, A. J. Sbatkin
  • 1992

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