Early stages of retinal development depend on Sec13 function

  title={Early stages of retinal development depend on Sec13 function},
  author={Katy Schmidt and Florencia Cavodeassi and Yi Min Feng and David John Stephens},
  booktitle={Biology open},
ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells. Nevertheless, there is emerging evidence that this process is regulated on a cell- and tissue-specific basis, which means that components of the COPII coat will be of differential importance to certain cell types. The COPII coat consists of an inner layer, Sec23/24 and an outer shell, Sec13/31. We have… CONTINUE READING
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