Early stages of oxidative stress-induced membrane permeabilization: a neutron reflectometry study.

@article{Smith2009EarlySO,
  title={Early stages of oxidative stress-induced membrane permeabilization: a neutron reflectometry study.},
  author={Hillary L. Smith and Michael C Howland and Alan W Szmodis and Qijuan Li and Luke L. Daemen and Atul N Parikh and Jaroslaw P. Majewski},
  journal={Journal of the American Chemical Society},
  year={2009},
  volume={131 10},
  pages={3631-8}
}
Neutron reflectometry was used to probe in situ the structure of supported lipid bilayers at the solid-liquid interface during the early stages of UV-induced oxidative degradation. Single-component supported lipid bilayers composed of gel phase, dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and fluid phase, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), phospholipids were exposed to low-dose oxidative stress generated by UV light and their structures were examined by neutron… CONTINUE READING

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