Early stage detection of conduit artery endothelial dysfunction in patients with type 1 diabetes.

  title={Early stage detection of conduit artery endothelial dysfunction in patients with type 1 diabetes.},
  author={J{\'e}r{\'e}my Bellien and Agathe Costentin and Benedicte Dutheil-Maillochaud and Mich{\`e}le Iacob and J W Kuhn and Christian Thuillez and Robinson Joannid{\`e}s},
  journal={Diabetes & vascular disease research},
  volume={7 2},
Flow-mediated dilatation evaluation using hand skin heating may possibly be more accurate than post-ischaemic hyperaemia to detect conduit artery endothelial dysfunction in type 1 diabetes. We measured in 24 type 1 diabetic patients (n=16 without microangiopathy) and 24 healthy matched subjects radial artery diameter (echotracking), blood flow and mean wall shear stress during heating and post-ischaemic hyperaemia. Compared with controls, flow-mediated dilatation was lower in diabetic patients… CONTINUE READING


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