Early social and physical deprivation leads to reduced social motivation in adulthood in Wistar rats

@article{Mintz2005EarlySA,
  title={Early social and physical deprivation leads to reduced social motivation in adulthood in Wistar rats},
  author={Matti Mintz and Daniela R{\"u}edi-Bettschen and Joram Feldon and Christopher R. Pryce},
  journal={Behavioural Brain Research},
  year={2005},
  volume={156},
  pages={311-320}
}
Behavioural abnormalities in adulthood may have their origin in a disturbed interaction with the environment during postnatal development. We tested the consequences for adult social motivation of early deprivation (ED) of rat pups from mothers and littermates relative to nonhandled (NH) pups. Early deprivation was performed at room or warm ambient temperatures, cold-ED and warm-ED, respectively, and during either the dark or light phase of the daily cycle. In adulthood, rats that were… CONTINUE READING
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