Early rise of anti-pseudomonas antibodies and a mucoid phenotype of pseudomonas aeruginosa are risk factors for development of chronic lung infection--a case control study.

@article{Pressler2006EarlyRO,
  title={Early rise of anti-pseudomonas antibodies and a mucoid phenotype of pseudomonas aeruginosa are risk factors for development of chronic lung infection--a case control study.},
  author={Tacjana Pressler and Birgitte Lidegaard Frederiksen and Marianne Nielsine Skov and Peter Garred and Christian Koch and Niels H{\o}iby},
  journal={Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society},
  year={2006},
  volume={5 1},
  pages={
          9-15
        }
}
P. aeruginosa is the most significant pathogen in CF lung disease. Chronic infection is preceded by a period of intermittent colonization. Early aggressive antimicrobial treatment at initial detection of P. aeruginosa in lower respiratory tract (LRT) secretions can prevent transition to chronic infection in approximately 80% of the patients, while the rest progress to chronic infection in spite of treatment. To analyze risk factors for development of chronic infection, a cohort of 89 CF… CONTINUE READING
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