Early response of gene clusters is associated with mouse lung resistance or sensitivity to cigarette smoke.

Abstract

We have investigated the effects of cigarette smoke exposure in three different strains of mice. DBA/2 and C57BL/6J are susceptible to smoke and develop different lung changes in response to chronic exposure, whereas ICR mice are resistant to smoke and do not develop emphysema. The present study was carried out to determine early changes in the gene… (More)
DOI: 10.1152/ajplung.90382.2008

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