Early response of endogenous adult neural progenitor cells to acute spinal cord injury in mice.

@article{Ke2006EarlyRO,
  title={Early response of endogenous adult neural progenitor cells to acute spinal cord injury in mice.},
  author={Yan Ke and Liying Chi and Renshi Xu and Chun Luo and David Gozal and Rugao Liu},
  journal={Stem cells},
  year={2006},
  volume={24 4},
  pages={
          1011-9
        }
}
Adult neural progenitor cells (NPCs) are an attractive source for functional replacement in neurodegenerative diseases and traumatic injury to the central nervous system (CNS). It has been shown that transplantation of neural stem cells or NPCs into the lesioned region partially restores CNS function. However, the capacity of endogenous NPCs in replacement of neuronal cell loss and functional recovery of spinal cord injury (SCI) is apparently poor. Furthermore, the temporal and spatial response… CONTINUE READING
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