Early response assessment in prostate carcinoma by 18F-fluorothymidine following anticancer therapy with docetaxel using preclinical tumour models

Abstract

The aim of the study was to assess the potential usefulness of 3-deoxy-3-18F-fluorothymidine (FLT) as a radiopharmaceutical for imaging the early therapeutic effects of docetaxel (DTX) on tumour proliferation in hormone-refractory prostate cancer (HRPC). Cells of the androgen-independent human prostate tumour cell line, 22Rv1, were implanted in athymic male… (More)
DOI: 10.1007/s00259-010-1613-z

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