Early regional changes of GFAP mRNA in rat hippocampus and dentate gyrus during soman-induced seizures.

@article{Crom1995EarlyRC,
  title={Early regional changes of GFAP mRNA in rat hippocampus and dentate gyrus during soman-induced seizures.},
  author={V Baille-Le Crom and J. M. Collombet and Pierre Carpentier and Guy Brochier and M. F. Burckhart and Annie Foquin and I Pernot-Marino and G{\'e}rard Rondouin and Guy Lallement},
  journal={Neuroreport},
  year={1995},
  volume={7 1},
  pages={365-9}
}
We investigated the time course of GFAP levels in the hippocampal formation during the first 24 h following soman intoxication in rats. GFAP mRNA expression was detected by in situ hybridization. Intense GFAP mRNA expression was present in the molecular layer of the dentate gyrus as early as 6 h after intoxication. This expression was comparatively lower in other dentate gyrus layers and hippocampal CA1, CA3 and CA4 areas and seemed to be related to excessive neuronal activity… CONTINUE READING
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