Early proctoscopy is a surrogate endpoint of late rectal toxicity in prostate cancer treated with radiotherapy.

@article{Ippolito2012EarlyPI,
  title={Early proctoscopy is a surrogate endpoint of late rectal toxicity in prostate cancer treated with radiotherapy.},
  author={Edy Ippolito and Mariangela Massaccesi and Cinzia Diges{\'u} and Francesco Deodato and Gabriella Macchia and Giuseppe Antonio Pirozzi and Savino Cilla and Daniele Cuscun{\`a} and Alessandra Di Lallo and Gian Carlo Mattiucci and Giovanna Mantini and F. Pacelli and Vincenzo Valentini and Numa Cellini and Marcello Ingrosso and Alessio Giuseppe Morganti},
  journal={International journal of radiation oncology, biology, physics},
  year={2012},
  volume={83 2},
  pages={
          e191-5
        }
}
PURPOSE To predict the grade and incidence of late clinical rectal toxicity through short-term (1 year) mucosal alterations. METHODS AND MATERIALS Patients with prostate adenocarcinoma treated with curative or adjuvant radiotherapy underwent proctoscopy a year after the course of radiotherapy. Mucosal changes were classified by the Vienna Rectoscopy Score (VRS). Late toxicity data were analyzed according to the Kaplan-Meier method. Comparison between prognosis groups was performed by log-rank… CONTINUE READING
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