Early pregnancy vaginal microbiome trends and preterm birth.

  title={Early pregnancy vaginal microbiome trends and preterm birth.},
  author={Molly J Stout and Yanjiao Zhou and Kristine M. Wylie and Phillip I Tarr and George A. Macones and Methodius G. Tuuli},
  journal={American journal of obstetrics and gynecology},
  volume={217 3},
BACKGROUND Despite decades of attempts to link infectious agents to preterm birth, an exact causative microbe or community of microbes remains elusive. Nonculture 16S ribosomal RNA gene sequencing suggests important racial differences and pregnancy specific changes in the vaginal microbial communities. A recent study examining the association of the vaginal microbiome and preterm birth documented important findings but was performed in a predominantly white cohort. Given the important racial… CONTINUE READING