Early pregnancy factor is immunosuppressive

@article{Noonan1979EarlyPF,
  title={Early pregnancy factor is immunosuppressive},
  author={Frances P. Noonan and William J. Halliday and Halle Morton and Gordon J. A. Clunie},
  journal={Nature},
  year={1979},
  volume={278},
  pages={649-651}
}
IMMUNOSUPPRESSION during pregnancy has important consequences not only with respect to the recognition of the antigenically dissimilar embryo1 but also in terms of susceptibility to viral or tumour assaults2,3. We have recently described an early pregnancy factor (EPF) detectable within 24 h of mating and have postulated that this protein is responsible for depression of lymphocyte activity during pregnancy4–6, Immunosuppressive properties have been attributed to other proteins detectable… CONTINUE READING

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