Early predictors of oxaliplatin-induced cumulative neuropathy in colorectal cancer patients.

@article{Velasco2014EarlyPO,
  title={Early predictors of oxaliplatin-induced cumulative neuropathy in colorectal cancer patients.},
  author={Roser Velasco and Jordi Bruna and C Briani and Andreas A. Argyriou and Guido Cavaletti and Paola Alberti and Barbara Frigeni and Mario Cacciavillani and Sara Lonardi and Diego Luigi Cortinovis and Marina Cazzaniga and Cristina Maria B. Santos and Haralambos P. Kalofonos},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2014},
  volume={85 4},
  pages={392-8}
}
OBJECTIVES Peripheral neuropathy ranks among the most common dose-limiting and disabling side-effect of oxaliplatin (OXA)-based chemotherapy. The aim of this prospective, multicentre study was to define early clinical and neurophysiological markers that may help to identify patients at risk of developing severe, treatment emergent, cumulative OXA-induced peripheral neuropathy (OXAIPN). METHODS 200 colorectal cancer patients, scheduled to receive OXA-based chemotherapy, were prospectively… CONTINUE READING
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