Early postnatal appearance of enhanced noradrenaline content in the brain of vasopressin-deficient Brattleboro rat; normal adrenoceptor densities and aberrant influences of vasopressin treatment.

@article{Boer1995EarlyPA,
  title={Early postnatal appearance of enhanced noradrenaline content in the brain of vasopressin-deficient Brattleboro rat; normal adrenoceptor densities and aberrant influences of vasopressin treatment.},
  author={G. J. Meeuwsen-de Boer and M. Feenstra and M J Botterblom and V Korse and Paula te Riele},
  journal={International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience},
  year={1995},
  volume={13 2},
  pages={63-74}
}
The course of postnatal development of noradrenaline (NA) and its unconjugated free metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG), as well as the influence on early chronic vasopressin treatment, were investigated in various brain regions of the hereditary vasopressin-deficient (homozygous di/di) Brattleboro rat. In addition, the densities of the adrenergic receptor subtypes were measured in adult brain. Brain NA levels of di/di pups appeared enhanced already at 7 days of age when compared… CONTINUE READING