Early polymorphonuclear leukocyte accumulation correlates with the development of posttraumatic cerebral edema in rats.

@article{Schoettle1990EarlyPL,
  title={Early polymorphonuclear leukocyte accumulation correlates with the development of posttraumatic cerebral edema in rats.},
  author={R J Schoettle and Patrick M Kochanek and M J Magargee and Mark Uhl and Edwin M. Nemoto},
  journal={Journal of neurotrauma},
  year={1990},
  volume={7 4},
  pages={207-17}
}
To evaluate the role of polymorphonuclear leukocytes (PMNs) in the development of posttraumatic cerebral edema, we quantitatively assessed the time course and magnitude of PMN accumulation and its relationship to cerebral edema formation after cerebral trauma in 78 rats. 111In-labeled PMN accumulation was measured in 26 rats in the first 8 h after right hemispheric percussive cerebral trauma or a sham control condition. 51Cr-labeled erythrocyte accumulation was measured simultaneously in 22… CONTINUE READING