Early passage bone marrow stromal cells express genes involved in nervous system development supporting their relevance for neural repair.

@article{Tewarie2011EarlyPB,
  title={Early passage bone marrow stromal cells express genes involved in nervous system development supporting their relevance for neural repair.},
  author={Rishi D. S. Nandoe Tewarie and Koen A M Bossers and Gaby J Ritfeld and Bas Blits and J Andre Grotenhuis and Joost Verhaagen and Martin Oudega},
  journal={Restorative neurology and neuroscience},
  year={2011},
  volume={29 3},
  pages={187-201}
}
PURPOSE The assessment of the capacity of bone marrow stromal cells (BMSC) to repair the nervous system using gene expression profiling. The evaluation of effects of long-term culturing on the gene expression profile of BMSC. METHODS Fourty four k whole genome rat microarrays were used to study gene expression of cultured BMSC at passage (P)3 and to compare expression profiles between P3 and P14 BMSC. Quantitative PCR was employed to validate the microarray results. RESULTS P3 BMSC… CONTINUE READING

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