Early outcomes after allogeneic hematopoietic SCT in pediatric patients with hematologic malignancies following single fraction TBI

@article{Druley2009EarlyOA,
  title={Early outcomes after allogeneic hematopoietic SCT in pediatric patients with hematologic malignancies following single fraction TBI},
  author={Todd E Druley and R J Hayashi and David B. Mansur and Qingling Zhang and Yvonne J. Barnes and Kathryn Trinkaus and S Witty and Terry Thomas and Eric E. Klein and John F. DiPersio and Dr Julie C. Adkins and Shalini Shenoy},
  journal={Bone Marrow Transplantation},
  year={2009},
  volume={43},
  pages={307-314}
}
Fractionated TBI (FTBI) followed by allogeneic hematopoietic SCT results in donor engraftment and improves survival in children with high-risk hematologic malignancies. However, acute toxicities (skin, lung and mucosa) are common after FTBI. Late complications include cataracts, endocrine dysfunction, sterility and impaired neurodevelopment. Instead of FTBI… CONTINUE READING