Early onset systemicCandida infection in extremely preterm neonates


Classically, systemicCandida infections in preterm neonates occur at a mean age of 1 month. Over an 18-month period in a Regional Neonatal Intensive Care Unit we encountered seven cases of severeCandida infection, all in babies below 26 weeks gestation and weighing less than 0.75 kg. The median age of onset was 7 days (range 0–17), with thrombocytopenia, coagulopathy, hypotension, oedema, and skin breakdown being prominent features.

DOI: 10.1007/BF02282843

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@article{Melville1996EarlyOS, title={Early onset systemicCandida infection in extremely preterm neonates}, author={Craig Andrew Melville and Stephen Terence Kempley and Jeffery Graham and Celia L Berry}, journal={European Journal of Pediatrics}, year={1996}, volume={155}, pages={904-906} }