Early onset of selective serotonin reuptake inhibitor antidepressant action: systematic review and meta-analysis.

@article{Taylor2006EarlyOO,
  title={Early onset of selective serotonin reuptake inhibitor antidepressant action: systematic review and meta-analysis.},
  author={Matthew J Taylor and Nick Freemantle and John R. Geddes and Zubin Bhagwagar},
  journal={Archives of general psychiatry},
  year={2006},
  volume={63 11},
  pages={1217-23}
}
CONTEXT Selective serotonin reuptake inhibitors (SSRIs) are often described as having a delayed onset of effect in the treatment of depression. However, some trials have reported clinical improvement as early as the first week of treatment. OBJECTIVE To test the alternative hypotheses of delayed vs early onset of antidepressant action with SSRIs in patients with unipolar depression. DATA SOURCES Trials identified by searching CENTRAL, The Cochrane Collaboration database of controlled trials… CONTINUE READING
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