Early-onset myasthenia gravis: Clinical characteristics and response to therapy

  title={Early-onset myasthenia gravis: Clinical characteristics and response to therapy},
  author={Anna Paola Batocchi and Amelia Evoli and M. T. Palmisani and Mauro Lo Monaco and M. Bartoccioni and Pietro Altilio Tonali},
  journal={European Journal of Pediatrics},
We studied 59 children with myasthenia gravis (MG). Disease onset was pre-pubertal in 26 patients and post-pubertal in 33. The male to female ratio was 0.62 in the early- and 0.17 in the late-onset groups. The frequency of ocular MG was higher in patients with prepubertal onset. Patients with generalized MG generally showed a good response to thymectomy and corticosteroid therapy proved effective with no major side-effects. In our experience early-onset MG has the same course as in adult life… CONTINUE READING


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