Early oligomerization stages for the non-amyloid component of α-synuclein amyloid.

@article{Eugene2014EarlyOS,
  title={Early oligomerization stages for the non-amyloid component of α-synuclein amyloid.},
  author={Cindie Eugene and Rozita Laghaei and Normand Mousseau},
  journal={The Journal of chemical physics},
  year={2014},
  volume={141 13},
  pages={135103}
}
In recent years, much effort has focused on the early stages of aggregation and the formation of amyloid oligomers. Aggregation processes for these proteins are complex and their non-equilibrium nature makes any experimental study very difficult. Under these conditions, simulations provide a useful alternative for understanding the dynamics of the early stages of oligomerization. Here, we focus on the non-Aβ amyloid component (NAC) of the monomer, dimer, and trimer of α-synuclein, an important… CONTINUE READING