Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma

@article{Chamberlain2006EarlyNF,
  title={Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma},
  author={Marc C Chamberlain and Michael J. Glantz and Lisa M Chalmers and Alixis Van Horn and Andrew E. Sloan},
  journal={Journal of Neuro-Oncology},
  year={2006},
  volume={82},
  pages={81-83}
}
Concurrent temozolomide (TMZ) and radiotherapy is the new standard of care for patients with newly diagnosed glioblastoma. In 51 consecutive patients treated according to this regimen, 7 patients (14%) manifested surgically confirmed early necrosis without evidence of recurrent tumor. This observation suggests that daily TMZ may represent a potent radiosensitizing regimen. 
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