Early necrosis and apoptosis of Schwann cells transplanted into the injured rat spinal cord.

@article{Hill2007EarlyNA,
  title={Early necrosis and apoptosis of Schwann cells transplanted into the injured rat spinal cord.},
  author={Caitlin E. Hill and Andr{\'e}s Esteban L{\'o}pez Hurtado and Bas Blits and Ben A Bahr and Patrick McGhee Wood and Mary Bartlett Bunge and Martin Oudega},
  journal={The European journal of neuroscience},
  year={2007},
  volume={26 6},
  pages={
          1433-45
        }
}
Poor survival of cells transplanted into the CNS is a widespread problem and limits their therapeutic potential. Whereas substantial loss of transplanted cells has been described, the extent of acute cell loss has not been quantified previously. To assess the extent and temporal profile of transplanted cell death, and the contributions of necrosis and apoptosis to this cell death following spinal cord injury, different concentrations of Schwann cells (SCs), lentivirally transduced to express… CONTINUE READING
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