Early motor disturbances in Rett syndrome and its pathophysiological importance

@article{Segawa2005EarlyMD,
  title={Early motor disturbances in Rett syndrome and its pathophysiological importance},
  author={M. Segawa},
  journal={Brain and Development},
  year={2005},
  volume={27},
  pages={s54-s58}
}
  • M. Segawa
  • Published 2005
  • Psychology, Medicine
  • Brain and Development
Assessment of the development of motor function of Rett syndrome (RTT) revealed hypotonia with failure of crawling and disturbance in skillful hand manipulation are shown as early motor signs. Clinical evaluation has revealed the former as postural hypotonia with failure in locomotion and neurophysiological examinations have showed this to be due to hypofunction of the aminergic neurons of the brainstem. The latter signs are considered to indicate dysfunction of the corticospinal tract at… Expand
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    References

    SHOWING 1-10 OF 36 REFERENCES
    Pathophysiology of Rett syndrome from the stand point of clinical characteristics
    • 24
    Characteristics of motor disturbances of the Rett syndrome
    • 39
    Discussant – pathophysiologies of Rett syndrome
    • M. Segawa
    • Medicine, Biology
    • Brain and Development
    • 2001
    • 24
    Rett syndrome—Clinical studies and pathophysiological consideration
    • 126
    Motor symptoms of the Rett syndrome: abnormal muscle tone, posture, locomotion and stereotyped movement.
    • 37
    Anatomy of Rett syndrome.
    • 29
    [Neuropathology and immunohistochemistry of brains with Rett syndrome].
    • 15
    Excitotoxic lesions of the pedunculopontine tegmental nucleus produce contralateral hemiparkinsonism in the monkey
    • 157
    Assessment of the maturity-related brainstem functions reveals the heterogeneous phenotypes and facilitates clinical management of Rett syndrome
    • 55
    Polysomnography in the Rett syndrome.
    • 40
    ...
    1
    2
    3
    4
    ...